Study shows DHA improves memory in mild cognitive impaitment

January 2013


To determine if docosahexaenoic acid (DHA) safely improves cognitive function in Malay and Chinese people with mild cognitive impairment (MCI) associated with age.

Study 1 Design:

  • Randomized, double-blind, placebocontrolled clinical trial
  • 36 low-socioeconomic-status elderly Malay and Chinese subjects with MCI (mean age 66.4 yrs +/- 5. yrs in the DHA group and 63.5 +/- 3 yrs in the placebo group)
  • Took the took 1.3 g DHA + 0.45 g EPA daily or a corn oil placebo for 12 months.

Study 1 Assessments:

Before and after treatment all participants were assessed for brain function and overall health using a variety tests as follows:

  • Primary endpoints
    • Memory
    • Executive function and attention
    • Psychomotor speed
    • Visiospatial skills
    • Depression
    • Dementia and Global Cognitive function
  • Secondary endpoints
    • Safety and tolerability

* The active DHA product provided was the high DHA oil that is the lead active ingredient in Efalex Active Memory and Efalex Concentrate.


DHA supplementation significantly improved memory function in people with mild cognitive impairment associated with age.

  • This was the first study specifically designed to measure cognitive improvements (rather than prevention of decline) in people with mild cognitive impairment.

For more Information: Call +44 (0) 1924 262 779 or Visit Efamol Ltd., Unit A, Cedar Court Office Park, Denby Dale Road, Wakefield, WF4 3QZ

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